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Systems biology of epigenetics and cell fate

Special Interest Symposium

Saturday, 5 September, 09:00-17:00 Hall 10B

This one-day symposium will be focused on recent developments in Computational Systems Biology of Epigenetics and Cell Fate. The symposium will bring computational and experimental systems biologist together to attend a series of talks by pioneers in the field.

The goals are to communicate recent success stories of collaboration between computational and experimental to reveal insights on the epigenetics regulation of cell fate, extend the network of computational biologists interested in epigenetics and cell fate started by EpiGeneSys, including UK and European scientists, provide opportunities for young researchers for communicating their work with more experienced researchers. The day will comprise presentations from invited senior scientists and selected from the participants.

This symposium is kindly supported by:

The Symposium is organised by associate members of EpiGeneSys, Nicolas Le NovèrePınar Pir (Babraham Institute, Cambridge) and Martin Howard (John Innes Centre, Norwich).


08:30-09:00 Welcome to the participants
Session 1 Leonie Ringrose Epigenetic marks
09:00-09:30 Martin Howard
John Innes Institute, Norwich
Dissecting quantitative Polycomb-based epigenetics through mathematical modelling and experiments
09:30-10:00 Christoph Bock
Research Center for Molecular Medicine (CeMM), Vienna
Dissecting cancer by epigenomics and single-cell sequencing
10:00-10:15 Reinhard Brunmeir
Singapore Institute for Clinical Sciences
Comparative epigenomic and transcriptomic analysis of white and brown adipogensis as a tool to discover novel adipogenic regulators
10:15-10:30 Discussion  
10:30-11:00 Coffee break
Session 2 Martin Howard Chromatin
11:00-11:30 Leonie Ringrose
Institute of Molecular Biotechnology, Vienna
Analog enhancer meets digital Polycomb Response Element
11:30-12:00 Karen Lipkow
Babraham Institute, Cambridge
Cellular Systems Biology of Chromosome Dynamics
12:00-12:15 Diagenode  
12:15-12:30 Discussion  
12:30-13:30 Lunch
Session 3 Alfonso Martinez-Arias Transcriptional regulation
13:30-14:00 Mikhail Spivakov
Babraham Institute, Cambridge
Probing human genomic regulatory architecture with Promoter Capture-HiC
14:00-14:30 Sara-Jane Dunn
Microsoft Research, Cambridge
Uncovering biological computation in embryonic stem cells
14:30-14:45 Subhendu Roy Choudhury
University of Birmingham
Exon Junction Complex (EJC) associates with transcription sites independently of splicing in Drosophila melanogaster
14:45-15:00 Discussion  
15:00-15:30 Coffee break
Session 4 Mikhail Spivakov Lineage determination
15:30-16:00 Alfonso Martinez-Arias
Cambridge University
Origin and function of heterogeneities in populations of mouse ES cells
16:00-16:30 Ingmar Glauche
Technical University, Dresden
Heterogeneity and cell fate control in mouse embryonic stem cells
16:30-16:45 Tahsin Stefan Barakat
University of Edinburgh
Stable X chromosome reactivation in female human induced pluripotent stem cells
16:45-17:00 Discussion  

Please note that participants wishing to attend the special interest symposium must register to attend The EMBO Meeting - day passes for Saturday 5 September are available. Conference registration is now open. Early deadline is 10 June.

Due to limited spaces available for this symposium, early reservation is recommended by This email address is being protected from spambots. You need JavaScript enabled to view it. . Participants who wish to give an oral presentation should send abstracts. Selected speakers will be announced shortly after the registration deadline.