Systems biology of epigenetics and cell fate

Special Interest Symposium

Saturday, 5 September, 09:00-17:00 Hall 10B

This one-day symposium will be focused on recent developments in Computational Systems Biology of Epigenetics and Cell Fate. The symposium will bring computational and experimental systems biologist together to attend a series of talks by pioneers in the field.

The goals are to communicate recent success stories of collaboration between computational and experimental to reveal insights on the epigenetics regulation of cell fate, extend the network of computational biologists interested in epigenetics and cell fate started by EpiGeneSys, including UK and European scientists, provide opportunities for young researchers for communicating their work with more experienced researchers. The day will comprise presentations from invited senior scientists and selected from the participants.

This symposium is kindly supported by:

The Symposium is organised by associate members of EpiGeneSys, Nicolas Le Novère, Pınar Pir (Babraham Institute, Cambridge) and Martin Howard (John Innes Centre, Norwich).

Programme

Time	Speaker/chair	Title
08:30-09:00	Welcome to the participants
*Session 1*	Leonie Ringrose	Epigenetic marks
09:00-09:30	Martin Howard John Innes Institute, Norwich	Dissecting quantitative Polycomb-based epigenetics through mathematical modelling and experiments
09:30-10:00	Christoph Bock Research Center for Molecular Medicine (CeMM), Vienna	Dissecting cancer by epigenomics and single-cell sequencing
10:00-10:15	Reinhard Brunmeir Singapore Institute for Clinical Sciences	Comparative epigenomic and transcriptomic analysis of white and brown adipogensis as a tool to discover novel adipogenic regulators
10:15-10:30	Discussion

10:30-11:00	Coffee break

*Session 2*	Martin Howard	Chromatin
11:00-11:30	Leonie Ringrose Institute of Molecular Biotechnology, Vienna	Analog enhancer meets digital Polycomb Response Element
11:30-12:00	Karen Lipkow Babraham Institute, Cambridge	Cellular Systems Biology of Chromosome Dynamics
12:00-12:15	Diagenode
12:15-12:30	Discussion

12:30-13:30	Lunch

*Session 3*	Alfonso Martinez-Arias	Transcriptional regulation
13:30-14:00	Mikhail Spivakov Babraham Institute, Cambridge	Probing human genomic regulatory architecture with Promoter Capture-HiC
14:00-14:30	Sara-Jane Dunn Microsoft Research, Cambridge	Uncovering biological computation in embryonic stem cells
14:30-14:45	Subhendu Roy Choudhury University of Birmingham	Exon Junction Complex (EJC) associates with transcription sites independently of splicing in Drosophila melanogaster
14:45-15:00	Discussion

15:00-15:30	Coffee break

Session 4	Mikhail Spivakov	Lineage determination
15:30-16:00	Alfonso Martinez-Arias Cambridge University	Origin and function of heterogeneities in populations of mouse ES cells
16:00-16:30	Ingmar Glauche Technical University, Dresden	Heterogeneity and cell fate control in mouse embryonic stem cells
16:30-16:45	Tahsin Stefan Barakat University of Edinburgh	Stable X chromosome reactivation in female human induced pluripotent stem cells
16:45-17:00	Discussion

Please note that participants wishing to attend the special interest symposium must register to attend The EMBO Meeting - day passes for Saturday 5 September are available. Conference registration is now open. Early deadline is 10 June.

Due to limited spaces available for this symposium, early reservation is recommended by This email address is being protected from spambots. You need JavaScript enabled to view it. . Participants who wish to give an oral presentation should send abstracts. Selected speakers will be announced shortly after the registration deadline.